The Double Helix: A Personal Account of the Discovery of the Structure of DNA
The classic personal account of Watson and Crick’s groundbreaking discovery of the structure of DNA, now with an introduction by Sylvia Nasar, author of A Beautiful Mind.
By identifying the structure of DNA, the molecule of life, Francis Crick and James Watson revolutionized biochemistry and won themselves a Nobel Prize. At the time, Watson was only twenty-four, a young scientist hungry to make his mark. His uncompromisingly honest account of the heady days of their thrilling sprint against other world-class researchers to solve one of science’s greatest mysteries gives a dazzlingly clear picture of a world of brilliant scientists with great gifts, very human ambitions, and bitter rivalries.
With humility unspoiled by false modesty, Watson relates his and Crick’s desperate efforts to beat Linus Pauling to the Holy Grail of life sciences, the identification of the basic building block of life. Never has a scientist been so truthful in capturing in words the flavor of his work.
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Since the war , Chargaff and his students had been painstakingly analyzing
various DNA samples for the relative proportions of their purine and pyrimidine
bases . In all their DNA preparations the number of adenine ( A ) molecules was
Soon , however , I abandoned thinking at the molecular level and turned to the
much easier job of reading biochemical ... RNA , but I preferred to trust other
experiments showing that DNA molecules , once synthesized , are very very
Instead it would strongly suggest that one chain in each molecule had at some
earlier stage served as the template for the ... Then two new daughter strands are
made on the two parental templates , thereby forming two DNA molecules ...
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LibraryThing ReviewUser Review - pramodghuge - LibraryThing
A very personal account by the author James Watson on how he and his colleague Francis Crick with the help of others beat Linus Pauling to win the coveted Nobel prize for identifying the structure of ... Read full review
LibraryThing ReviewUser Review - ajlewis2 - LibraryThing
I read about a third of it. I found the story wandered and wasn't clear. His treatment of Rosalind Franklin sounded like something written in the 1950s. It was at that point that I decided the book ... Read full review