The Double Helix: A Personal Account of the Discovery of the Structure of DNA
The classic personal account of Watson and Crick’s groundbreaking discovery of the structure of DNA, now with an introduction by Sylvia Nasar, author of A Beautiful Mind.
By identifying the structure of DNA, the molecule of life, Francis Crick and James Watson revolutionized biochemistry and won themselves a Nobel Prize. At the time, Watson was only twenty-four, a young scientist hungry to make his mark. His uncompromisingly honest account of the heady days of their thrilling sprint against other world-class researchers to solve one of science’s greatest mysteries gives a dazzlingly clear picture of a world of brilliant scientists with great gifts, very human ambitions, and bitter rivalries.
With humility unspoiled by false modesty, Watson relates his and Crick’s desperate efforts to beat Linus Pauling to the Holy Grail of life sciences, the identification of the basic building block of life. Never has a scientist been so truthful in capturing in words the flavor of his work.
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... told him that it would occur in the keto form . He was just as sure that thymine was also wrongly assigned an enol configuration . Again he strongly favored the keto alternative . 190 ENOL KETO NO sugar sugar thymine N IN N Jerry.
Jerry , however , did not give a foolproof reason for preferring the keto forms . He admitted that only one crystal structure bore on the problem . This was diketopiperazine , whose three - dimensional configuration had been carefully ...
There was no questioning of the decision to put guanine and thymine in the keto form . Doing otherwise would destroy the base pairs , and he accepted Jerry Donohue's spoken argument as if it were a commonplace .
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LibraryThing ReviewUser Review - tgraettinger - LibraryThing
Wonderful account of the discovery of DNA. Had almost the feel of a detective novel. It's a very easy, quick read. If you can find it, there is a video, "The Race for the Double Helix" aka "Life Story ... Read full review
LibraryThing ReviewUser Review - pramodghuge - LibraryThing
A very personal account by the author James Watson on how he and his colleague Francis Crick with the help of others beat Linus Pauling to win the coveted Nobel prize for identifying the structure of ... Read full review