The Double Helix: A Personal Account of the Discovery of the Structure of DNA
The classic personal account of Watson and Crick’s groundbreaking discovery of the structure of DNA, now with an introduction by Sylvia Nasar, author of A Beautiful Mind.
By identifying the structure of DNA, the molecule of life, Francis Crick and James Watson revolutionized biochemistry and won themselves a Nobel Prize. At the time, Watson was only twenty-four, a young scientist hungry to make his mark. His uncompromisingly honest account of the heady days of their thrilling sprint against other world-class researchers to solve one of science’s greatest mysteries gives a dazzlingly clear picture of a world of brilliant scientists with great gifts, very human ambitions, and bitter rivalries.
With humility unspoiled by false modesty, Watson relates his and Crick’s desperate efforts to beat Linus Pauling to the Holy Grail of life sciences, the identification of the basic building block of life. Never has a scientist been so truthful in capturing in words the flavor of his work.
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Even the necessity to expunge Ecstasy from my mind did not lead to passable
hydrogen bonds, and I fell asleep hoping that an undergraduate party the next
afternoon at Downing would be full of pretty girls. But my expectations were
The metal purine and pyrimidine models, needed for systematically checking all
the conceivable hydrogen-bonding possibilities, had not been finished on time.
At least two more days were needed before they would be in our hands. This was
5-hydroxy-methyl cytosine should hydrogen-bond like cytosine. Also pleasing
was the great accuracy of the data, which illustrated better than any previous
analytical work the equality of adenine with thymine and guanine with cytosine.
While I ...
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THE DOUBLE HELIX: A Personal Account Of The Discovery Of The Structure Of DnaUser Review - Kirkus
Even without understanding any of the scientific data processed here, the general reader will find it hard to remain immune to this account of how J.D. Watson, along with another bright, volatile ... Read full review
LibraryThing ReviewUser Review - quantum_flapdoodle - LibraryThing
James Watson's love letter to himself, as he explains to us exactly how he single-handedly solved the structure of DNA, with the insignificant help of a cast of baboons, clowns, and women. Watson's ... Read full review