The Double Helix: A Personal Account of the Discovery of the Structure of DNA
The classic personal account of Watson and Crick’s groundbreaking discovery of the structure of DNA, now with an introduction by Sylvia Nasar, author of A Beautiful Mind.
By identifying the structure of DNA, the molecule of life, Francis Crick and James Watson revolutionized biochemistry and won themselves a Nobel Prize. At the time, Watson was only twenty-four, a young scientist hungry to make his mark. His uncompromisingly honest account of the heady days of their thrilling sprint against other world-class researchers to solve one of science’s greatest mysteries gives a dazzlingly clear picture of a world of brilliant scientists with great gifts, very human ambitions, and bitter rivalries.
With humility unspoiled by false modesty, Watson relates his and Crick’s desperate efforts to beat Linus Pauling to the Holy Grail of life sciences, the identification of the basic building block of life. Never has a scientist been so truthful in capturing in words the flavor of his work.
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... to be made whether the chains would be held together by hydrogen bonds or
by salt linkages involving the negatively charged phosphate groups . A further
complication arose from the fact that four types of nucleotides were found in DNA
As to the forces that held the chains together , the best guess seemed to be salt
bridges in which divalent cations like Mg ++ held together two or more phosphate
groups . Admittedly there was no evidence that Rosy's samples contained any ...
When I got to our still empty office the following morning , I quickly cleared away
the papers from my desk top so that I would have a large , flat surface on which to
form pairs of bases held together by hydrogen bonds . Though I initially went ...
What people are saying - Write a review
LibraryThing ReviewUser Review - tgraettinger - LibraryThing
Wonderful account of the discovery of DNA. Had almost the feel of a detective novel. It's a very easy, quick read. If you can find it, there is a video, "The Race for the Double Helix" aka "Life Story ... Read full review
LibraryThing ReviewUser Review - pramodghuge - LibraryThing
A very personal account by the author James Watson on how he and his colleague Francis Crick with the help of others beat Linus Pauling to win the coveted Nobel prize for identifying the structure of ... Read full review