The Double Helix: A Personal Account of the Discovery of the Structure of DNAThe classic personal account of Watson and Crick’s groundbreaking discovery of the structure of DNA, now with an introduction by Sylvia Nasar, author of A Beautiful Mind. By identifying the structure of DNA, the molecule of life, Francis Crick and James Watson revolutionized biochemistry and won themselves a Nobel Prize. At the time, Watson was only twenty-four, a young scientist hungry to make his mark. His uncompromisingly honest account of the heady days of their thrilling sprint against other world-class researchers to solve one of science’s greatest mysteries gives a dazzlingly clear picture of a world of brilliant scientists with great gifts, very human ambitions, and bitter rivalries. With humility unspoiled by false modesty, Watson relates his and Crick’s desperate efforts to beat Linus Pauling to the Holy Grail of life sciences, the identification of the basic building block of life. Never has a scientist been so truthful in capturing in words the flavor of his work. |
From inside the book
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Page 52
... held together by hydrogen bonds or by salt linkages involving the nega- tively charged phosphate groups . A further complication arose from the fact that four types of nucleotides were found in DNA . In this sense , DNA was not a ...
... held together by hydrogen bonds or by salt linkages involving the nega- tively charged phosphate groups . A further complication arose from the fact that four types of nucleotides were found in DNA . In this sense , DNA was not a ...
Page 88
... held the chains together , the best guess seemed to be salt bridges in which diva- lent cations like Mg ++ held together two or more phos- phate groups . Admittedly there was no evidence that Rosy's samples contained any divalent ions ...
... held the chains together , the best guess seemed to be salt bridges in which diva- lent cations like Mg ++ held together two or more phos- phate groups . Admittedly there was no evidence that Rosy's samples contained any divalent ions ...
Page 194
... held together by hydro- gen bonds . Though I initially went back to my like - with - like prejudices , I saw all too ... held together by two hydrogen bonds was identical in shape to a guanine - cytosine pair held together by at least ...
... held together by hydro- gen bonds . Though I initially went back to my like - with - like prejudices , I saw all too ... held together by two hydrogen bonds was identical in shape to a guanine - cytosine pair held together by at least ...
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Common terms and phrases
a-helix adenine answer argument arranged arrival atoms bacterial base pairs biochemistry biological Cal Tech Cambridge Cavendish chains Chargaff's Chargaff's rules chemical chemistry chemists College conversation Copenhagen crystallographic crystals cytosine Delbrück dinner DNA molecule DNA structure double helix Elizabeth existed experimental experiments fact fellowship Francis Crick genes genetic geneticists girls Griffith guanine Herman hope Hugh Huxley hydrogen bonds idea immediately important ions John Kendrew keto King's knew large number letter Linus Pauling London look lunch Luria manuscript Maurice Wilkins Maurice's Max and John Max Perutz ment model building molecular Moreover morning never Nonetheless nucleic acids nucleotides Odile Pauling's Perutz Peter phage phosphate groups polynucleotide Pop's possibility problem protein purine purine and pyrimidine pyrimidine quickly realized reason Rosalind Franklin Rosy Rosy's scientific solve soon sugar sugar-phosphate backbone talk tautomeric forms tell thought thymine tion told walked wanted Watson week X-ray photograph X-ray pictures