The Double Helix: A Personal Account of the Discovery of the Structure of DNAThe classic personal account of Watson and Crick’s groundbreaking discovery of the structure of DNA, now with an introduction by Sylvia Nasar, author of A Beautiful Mind. By identifying the structure of DNA, the molecule of life, Francis Crick and James Watson revolutionized biochemistry and won themselves a Nobel Prize. At the time, Watson was only twenty-four, a young scientist hungry to make his mark. His uncompromisingly honest account of the heady days of their thrilling sprint against other world-class researchers to solve one of science’s greatest mysteries gives a dazzlingly clear picture of a world of brilliant scientists with great gifts, very human ambitions, and bitter rivalries. With humility unspoiled by false modesty, Watson relates his and Crick’s desperate efforts to beat Linus Pauling to the Holy Grail of life sciences, the identification of the basic building block of life. Never has a scientist been so truthful in capturing in words the flavor of his work. |
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Page 182
... bases . Their formulas were written out in J. N. Davidson's little book The Biochemistry of Nucleic Acids , a copy of which I kept in Clare . So I could be sure that I had the correct structures when I drew tiny pictures of the bases on ...
... bases . Their formulas were written out in J. N. Davidson's little book The Biochemistry of Nucleic Acids , a copy of which I kept in Clare . So I could be sure that I had the correct structures when I drew tiny pictures of the bases on ...
Page 194
... bases out of stiff cardboard . But by the time they were ready I realized that the answer must be put off till the next day . After dinner I was to join a group from Pop's at the theater . When I got to our still empty office the ...
... bases out of stiff cardboard . But by the time they were ready I realized that the answer must be put off till the next day . After dinner I was to join a group from Pop's at the theater . When I got to our still empty office the ...
Page 219
... base pairs , thereby decreasing the translational dis- tance of a base pair along the fiber axis to about 2.6 Å . He thus set about building a model with tilted bases . Though this proved more difficult to fit together than the more ...
... base pairs , thereby decreasing the translational dis- tance of a base pair along the fiber axis to about 2.6 Å . He thus set about building a model with tilted bases . Though this proved more difficult to fit together than the more ...
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Common terms and phrases
a-helix adenine answer argument arranged arrival atoms bacterial base pairs biochemistry biological Cal Tech Cambridge Cavendish chains Chargaff's Chargaff's rules chemical chemistry chemists College conversation Copenhagen crystallographic crystals cytosine Delbrück dinner DNA molecule DNA structure double helix Elizabeth existed experimental experiments fact fellowship Francis Crick genes genetic geneticists girls Griffith guanine Herman hope Hugh Huxley hydrogen bonds idea immediately important ions John Kendrew keto King's knew large number letter Linus Pauling London look lunch Luria manuscript Maurice Wilkins Maurice's Max and John Max Perutz ment model building molecular Moreover morning never Nonetheless nucleic acids nucleotides Odile Pauling's Perutz Peter phage phosphate groups polynucleotide Pop's possibility problem protein purine purine and pyrimidine pyrimidine quickly realized reason Rosalind Franklin Rosy Rosy's scientific solve soon sugar sugar-phosphate backbone talk tautomeric forms tell thought thymine tion told walked wanted Watson week X-ray photograph X-ray pictures