The Double Helix: A Personal Account of the Discovery of the Structure of DNAThe classic personal account of Watson and Crick’s groundbreaking discovery of the structure of DNA, now with an introduction by Sylvia Nasar, author of A Beautiful Mind. By identifying the structure of DNA, the molecule of life, Francis Crick and James Watson revolutionized biochemistry and won themselves a Nobel Prize. At the time, Watson was only twenty-four, a young scientist hungry to make his mark. His uncompromisingly honest account of the heady days of their thrilling sprint against other world-class researchers to solve one of science’s greatest mysteries gives a dazzlingly clear picture of a world of brilliant scientists with great gifts, very human ambitions, and bitter rivalries. With humility unspoiled by false modesty, Watson relates his and Crick’s desperate efforts to beat Linus Pauling to the Holy Grail of life sciences, the identification of the basic building block of life. Never has a scientist been so truthful in capturing in words the flavor of his work. |
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Page xx
... 1951 Chemical structures of the DNA bases , 1951 Covalent bonds of the
sugar - phosphate backbone Schematic view of a nucleotide Mg ** ions binding
phosphate groups Schematic view of DNA , like - with - like base pairs Base pairs
for ...
... 1951 Chemical structures of the DNA bases , 1951 Covalent bonds of the
sugar - phosphate backbone Schematic view of a nucleotide Mg ** ions binding
phosphate groups Schematic view of DNA , like - with - like base pairs Base pairs
for ...
Page 196
make the two types of base pairs identical in shape . Quickly I called Jerry over to
ask him whether this time he had any objection to my new base pairs . When he
said no , my morale skyrocketed , for I suspected that we now had the answer to ...
make the two types of base pairs identical in shape . Quickly I called Jerry over to
ask him whether this time he had any objection to my new base pairs . When he
said no , my morale skyrocketed , for I suspected that we now had the answer to ...
Page 197
His quickly pushing the bases together in a number of different ways did not
reveal any other way to satisfy Chargaff's rules . A few minutes later he spotted
the fact that the two glycosidic bonds ( joining base and sugar ) of each base pair
were ...
His quickly pushing the bases together in a number of different ways did not
reveal any other way to satisfy Chargaff's rules . A few minutes later he spotted
the fact that the two glycosidic bonds ( joining base and sugar ) of each base pair
were ...
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LibraryThing Review
User Review - pramodghuge - LibraryThingA very personal account by the author James Watson on how he and his colleague Francis Crick with the help of others beat Linus Pauling to win the coveted Nobel prize for identifying the structure of ... Read full review
LibraryThing Review
User Review - ajlewis2 - LibraryThingI read about a third of it. I found the story wandered and wasn't clear. His treatment of Rosalind Franklin sounded like something written in the 1950s. It was at that point that I decided the book ... Read full review
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Common terms and phrases
acid adenine answer argument arranged arrival asked atoms backbone base pairs bases became began biological bonds Bragg building Cambridge Cavendish chemical chemistry coiled coils College completely conversation Crick crystallographic cytosine Delbrück double helix English equal evidence existed experiments face fact final Francis gave genes genetic give given groups guanine hand held helical hope hydrogen idea immediately important interest John join King's knew later letter Linus London look lunch Maurice meeting mind molecules months Moreover morning moved Nature needed never obvious Pauling Pauling's Peter position possibility problem protein quickly realized reason remained Rosy saying scientific sense solve soon structure success sugar sure talk tell theory thinking thought tion told walked wanted week X-ray