The Double Helix: A Personal Account of the Discovery of the Structure of DNA
The classic personal account of Watson and Crick’s groundbreaking discovery of the structure of DNA, now with an introduction by Sylvia Nasar, author of A Beautiful Mind.
By identifying the structure of DNA, the molecule of life, Francis Crick and James Watson revolutionized biochemistry and won themselves a Nobel Prize. At the time, Watson was only twenty-four, a young scientist hungry to make his mark. His uncompromisingly honest account of the heady days of their thrilling sprint against other world-class researchers to solve one of science’s greatest mysteries gives a dazzlingly clear picture of a world of brilliant scientists with great gifts, very human ambitions, and bitter rivalries.
With humility unspoiled by false modesty, Watson relates his and Crick’s desperate efforts to beat Linus Pauling to the Holy Grail of life sciences, the identification of the basic building block of life. Never has a scientist been so truthful in capturing in words the flavor of his work.
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They thought that all the internucleotide links were phosphodiester bonds joining
sugar carbon atom #5 to sugar carbon atom #3 of the adjacent nucleotide. As
organic chemists they were concerned with how the atoms were linked together,
They had been constructed by John some eighteen months before, for the work
on the threedimensional shape of the polypeptide chain. There existed no
accurate representations of the groups of atoms unique to DNA. Neither
One couldn't be sure, but the impression was there that any model placing the
sugar-phosphate backbone in the center of a helix forced atoms closer together
than the laws of chemistry allowed. Positioning one atom the proper distance
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THE DOUBLE HELIX: A Personal Account Of The Discovery Of The Structure Of DnaUser Review - Kirkus
Even without understanding any of the scientific data processed here, the general reader will find it hard to remain immune to this account of how J.D. Watson, along with another bright, volatile ... Read full review
LibraryThing ReviewUser Review - Devil_llama - LibraryThing
James Watson's love letter to himself, as he explains to us exactly how he single-handedly solved the structure of DNA, with the insignificant help of a cast of baboons, clowns, and women. Watson's ... Read full review