The Double Helix: A Personal Account of the Discovery of the Structure of DNA
The classic personal account of Watson and Crick’s groundbreaking discovery of the structure of DNA, now with an introduction by Sylvia Nasar, author of A Beautiful Mind.
By identifying the structure of DNA, the molecule of life, Francis Crick and James Watson revolutionized biochemistry and won themselves a Nobel Prize. At the time, Watson was only twenty-four, a young scientist hungry to make his mark. His uncompromisingly honest account of the heady days of their thrilling sprint against other world-class researchers to solve one of science’s greatest mysteries gives a dazzlingly clear picture of a world of brilliant scientists with great gifts, very human ambitions, and bitter rivalries.
With humility unspoiled by false modesty, Watson relates his and Crick’s desperate efforts to beat Linus Pauling to the Holy Grail of life sciences, the identification of the basic building block of life. Never has a scientist been so truthful in capturing in words the flavor of his work.
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They thought that all the internucleotide links were phosphodiester bonds joining sugar carbon atom # 5 to sugar carbon atom # 3 of the adjacent nucleotide . As organic chemists they were concerned with how the atoms were linked ...
There existed no accurate representations of the groups of atoms unique to DNA . Neither phosphorus atoms nor the purine and pyrimidine bases were on hand . Rapid improvisation would be necessary since there was no time for Max to give ...
One couldn't be sure , but the impression was there that any model placing the sugar - phosphate backbone in the center of a helix forced atoms closer together than the laws of chemistry allowed . Positioning one atom the proper ...
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LibraryThing ReviewUser Review - tgraettinger - LibraryThing
Wonderful account of the discovery of DNA. Had almost the feel of a detective novel. It's a very easy, quick read. If you can find it, there is a video, "The Race for the Double Helix" aka "Life Story ... Read full review
LibraryThing ReviewUser Review - pramodghuge - LibraryThing
A very personal account by the author James Watson on how he and his colleague Francis Crick with the help of others beat Linus Pauling to win the coveted Nobel prize for identifying the structure of ... Read full review