The Double Helix: A Personal Account of the Discovery of the Structure of DNAThe classic personal account of Watson and Crick’s groundbreaking discovery of the structure of DNA, now with an introduction by Sylvia Nasar, author of A Beautiful Mind. By identifying the structure of DNA, the molecule of life, Francis Crick and James Watson revolutionized biochemistry and won themselves a Nobel Prize. At the time, Watson was only twenty-four, a young scientist hungry to make his mark. His uncompromisingly honest account of the heady days of their thrilling sprint against other world-class researchers to solve one of science’s greatest mysteries gives a dazzlingly clear picture of a world of brilliant scientists with great gifts, very human ambitions, and bitter rivalries. With humility unspoiled by false modesty, Watson relates his and Crick’s desperate efforts to beat Linus Pauling to the Holy Grail of life sciences, the identification of the basic building block of life. Never has a scientist been so truthful in capturing in words the flavor of his work. |
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Page 8
... X - ray dif- fraction data from hemoglobin crystals for over ten years and was just beginning to get somewhere . Help- ing him was Sir Lawrence Bragg , the director of the Cavendish . For almost forty years Bragg , a Nobel Prize winner ...
... X - ray dif- fraction data from hemoglobin crystals for over ten years and was just beginning to get somewhere . Help- ing him was Sir Lawrence Bragg , the director of the Cavendish . For almost forty years Bragg , a Nobel Prize winner ...
Page 54
... X - ray evidence , he knew of its existence and to a certain extent had taken it into account . Given the X - ray data , a large variety of possible three- dimensional configurations for the polypeptide chain were quickly discarded ...
... X - ray evidence , he knew of its existence and to a certain extent had taken it into account . Given the X - ray data , a large variety of possible three- dimensional configurations for the polypeptide chain were quickly discarded ...
Page 137
... X - ray work with viruses . Virtually no words went to DNA . When I brought up the X - ray pictures at King's , Linus gave the opinion that very accurate X - ray work of the type done by his associates on amino acids was vital to our ...
... X - ray work with viruses . Virtually no words went to DNA . When I brought up the X - ray pictures at King's , Linus gave the opinion that very accurate X - ray work of the type done by his associates on amino acids was vital to our ...
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Common terms and phrases
a-helix adenine answer argument arranged arrival atoms bacterial base pairs biochemistry biological Cal Tech Cambridge Cavendish chains Chargaff's Chargaff's rules chemical chemistry chemists College conversation Copenhagen crystallographic crystals cytosine Delbrück dinner DNA molecule DNA structure double helix Elizabeth existed experimental experiments fact fellowship Francis Crick genes genetic geneticists girls Griffith guanine Herman hope Hugh Huxley hydrogen bonds idea immediately important ions John Kendrew keto King's knew large number letter Linus Pauling London look lunch Luria manuscript Maurice Wilkins Maurice's Max and John Max Perutz ment model building molecular Moreover morning never Nonetheless nucleic acids nucleotides Odile Pauling's Perutz Peter phage phosphate groups polynucleotide Pop's possibility problem protein purine purine and pyrimidine pyrimidine quickly realized reason Rosalind Franklin Rosy Rosy's scientific solve soon sugar sugar-phosphate backbone talk tautomeric forms tell thought thymine tion told walked wanted Watson week X-ray photograph X-ray pictures