Chemical Engineering Problems in Biotechnology

aeration affinity chromatography agitator air-lift amplifier animal cells baker's yeast batch biochemical engineer Bioengng biological biomass bioreactor Biotechnol biotechnology bubble column cell culture cell disruption Chem chemical concentration correlation damage density developed diameter diffusion disruption dissolved oxygen downstream processing effect Engng enzyme ethanol factor fed-batch fermentation broth fermentation processes fibres filter filtration flow rate fluidised bed gas hold-up gas-liquid growth growth medium heat transfer heat-transfer hollow-fibre immobilised impeller speed increasing industrial input laminar liquid phase litre loop measurement mechanical medium membrane methods microcarriers Moo-Young non-Newtonian fluids nutrient operation optimisation packed bed parameter particles penicillin power dissipation precipitation problems process variables protein reactor Reynolds number scale-up shear rate shear stress signal solid-liquid separation sparged specific growth rate stirred tanks stirred-tank fermenters stirrer speed substrate superficial gas velocity surface techniques tion turbulent ultrafiltration vessel viscosity volume volumetric mass-transfer coefficient Winkler