Frontiers in Clinical Drug Research - Anti-Allergy Agents, Volume 3Atta-ur-Rahman Frontiers in Clinical Drug Research - Anti-Allergy Agents is a book series comprising of a selection of updated review articles relevant to the recent development of pharmacological agents used for the treatment of allergies. The scope of the reviews includes clinical trials of anti-inflammatory and anti-allergic drugs, drug delivery strategies used to treat specific allergies (such as inflammation, asthma and dermatological allergies), lifestyle dependent modes of therapies and the immunological or metabolic mechanisms that are of interest to researchers as targets for new drugs. The third volume of this series brings 5 reviews which cover the following topics: H1 receptor selectivity, chronic spontaneous urticaria therapy, smooth muscle cell Ca2+ signaling pathway targeting for asthma therapy, allergic rhinitis and endosomal toll-like receptors. Frontiers in Clinical Drug Research - Anti-Allergy Agents will be of interest to immunologists and drug discovery researchers interested in anti-allergic drug therapy as the series provides relevant cutting edge reviews written by experts in this rapidly expanding field. |
Contents
A Voyage in H1 Selectivity | 1 |
Therapeutics in Chronic Spontaneous Urticaria | 96 |
Research and Development for AntiAsthmatic Agents with a Focus on Phenotype Changing by Ca2+ Signaling in Airway Smooth Muscle Cells | 116 |
Effects of Allergic Rhinitis on Communication Skills | 182 |
Rheostats of Inflammation and Diseases | 194 |
| 237 | |
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Common terms and phrases
acid activation adrenoceptor agents airway smooth muscle allergen allergic conjunctivitis Allergy Clin Immunol allosteric antihistamines asthma azelastine Ca2+ dynamics Ca2+ sensitization cancer cetirizine chronic idiopathic urticaria chronic urticaria colleagues conjunctival contractile contraction COPD cytokines demonstrated Dermatol desensitization desloratadine disease dose double blind RCT double-blind drug endosomal eosinophil exposure fexofenadine formoterol function G protein GPCR H1 receptor histamine human immune increased indacaterol induced inflammation inflammatory inhibition inhibitor intracellular intrinsic efficacy isoprenaline KCa channels ketotifen Kume H levocabastine levocetirizine ligands loratadine mast cells mediators membrane mice modulation molecules muscarinic receptor nasal olopatadine Omalizumab pathway patients Pharmacol phenotype phosphorylation Physiol piperidine placebo placebo-controlled PMID procaterol proliferation protein kinase receptor antagonist regulation relaxation release response Rho-kinase RhoA role salmeterol second generation antihistamines side effects signaling skin smooth muscle cells stimulation symptoms terfenadine therapeutic therapy TLR3 TLR7 TLR8 TLR9 tracheal smooth muscle treatment urticaria VDC channels