Bioinformatics is a computer-assisted interface discipline dealing with acquisition, storage, management, access and processing of biological data. Bioinformatics is useful in identifying genes in DNA sequences, in the study of structure and function of genes and protein sequences in identifying families of related sequences, in aligning similar sequences and generating phylogenetic trees, in discovering drug targets, and in drug development. This book is designed to provide the newcomer with enough information to understand the principles of bioinformatics applications.
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algorithm amino acid amino acid sequence annotations Bioinformatics biological blocks BLOSUM cDNA cell chain chemical chromosomes clone codons conserved contains database search disease distance DNA sequence domain drug dynamic programming EMBL encode enzyme eukaryotic evolutionary exons Expressed Sequence Tags FASTA fold fragments function GenBank gene expression gene prediction genetic genome project groups Hidden Markov Models homologous human genome identify interactions Internet introns known structures mapping matches matrix methods microarray molecular motifs mRNA multiple alignment multiple sequence alignment mutations NCBI nodes nucleic acid nucleotide sequence organisms package patterns phylogenetic analysis phylogenetic tree polypeptide positions profiles protein sequence protein structure proteomics Protocol provides query sequence regions related sequences relationships residues retrieval ribosomes rRNA score sequence analysis sequence data sequence databases server similar specific splice strand substitutions SWISS-PROT target template transcription translation tRNA types